SAFE-AMP 1: Microprocessor Knee Technology Reduces Odds of Incurring an Injurious Fall for Individuals with Diabetic/Dysvascular Amputation

January 11, 2022
Hanger Clinic


Assistive Technology
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Shane R. Wurdeman1,2, Taavy A. Miller1, 3, Phillip M. Stevens1,4, James H. Campbell1

  1. Department of Clinical and Scientific Affairs, Hanger Clinic, Austin, TX, USA
  2. Department of Biomechanics, University of Nebraska at Omaha, Omaha, NE, USA
  3. School of Public Health, University of North Carolina at Charlotte, Charlotte, NC, US
  4. School of Medicine, University of Utah, Salt Lake City, UT, USA


Although diabetes and dysvascular disease are the most common cause of amputations in the United States, the majority of research has focused on traumatic amputations. Stability and Falls Evaluation after AMPutation (SAFE-AMP) 1 is the first of a series of studies that will examine the need for greater access to appropriate rehabilitation solutions for below and above-knee amputees in the diabetes community. SAFE-AMP 1, conducted by members of the Hanger Institute for Clinical Research and Education, sought to evaluate the impact of microprocessor-controlled knees (MPKs) on rates of injurious falls among diabetic and dysvascular people with above-knee amputations.


An above-the-knee amputation and diabetes/vascular disease are both risk factors for falls. Microprocessor knee technology may reduce falls in this population. The objective of this study was to determine the association of MPKs and reduced injurious falls.


A retrospective analysis of injurious falls within a large, national outcomes database was conducted.

Patient Inclusion Criteria:

Table 1: Patient Demographics (n=881)


Results showed that 16.3% of non-MPK users experienced an injurious fall compared to 7.3% of MPK users (p=0.007).

Figure 1: Odds Ratios

While accounting for age, sex, time since amputation, and adjusted BMI, it was noted that individuals that are not provided an MPK have 2.52 times increased odds of sustaining an injurious fall over a 6-month period compared to their counterparts that receive an MPK.


Meet the SAFE-AMP 1 Authors

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